The macrozoobenthos dataset includes a number of 106 samples collected in the Northern part of the Romanian littoral from 5 m to 70 m depths. Van Veen grab with a sampling area of 1/20 m2 was employed as a macrozoobenthos sampler. One replicate was collected at every station. The samples have been analyzed qualitative and quantitative. The macroinvertebrates have been identified at the species level. Dataset contains abundance (ind/m2) and biomass (g/m2) data.