This data contains 63 geolocated water stable isotopes and salinity measurements from the surface of the ocean along the RV Oden cruise track. Surface seawater sampling was conducted using bucket sampling. This was done by throwing a weighted bucket offboard to sample the surface of the ocean every six (6) hours. Chosen times were 5:00, 11:00, 17:00, and 23:00. Multiple readings of sea surface salinity were recorded using a YSI professional series digital probe per sampling Water samples were transferred to a 30-mL Nalgene bottles that were filled to the brim. Bottles were tightly closed, sealed with parafilm, and placed inside sampling bags. Two samples were collected per sampling point, and all measurements were geolocated. A total of 126 samples were collected from 19 July – 04 August 2019. All water samples were transported to the Atmosphere, Climate, and Ecosystems lab at the University of Illinois at Chicago for processing. The δ¹⁸O and dD were measured using a Picarro l2130-I CRDS water isotope analyzer with a wire mesh inserted in the vaporizer inlet to trap salt from the seawater. Fifteen injections were made for each sample and necessary corrections to address 'memory effect' were employed. Measurements were normalized using the dD and δ¹⁸O values of internal water standards. Data table header includes the event, latitude, longitude, sampling date, campaign, sampling method, location, isotope analyzer model, salinity sensor, ¹⁸O values (‰), D values (‰), and salinity values (psu).