The MesuRho station is a multi-parameter observing platform located at the Rhone River mouth and installed on a navigation buoy, Roustan Est. It is dedicated to the study of trends and impacts of extreme events (floods, storms, heat waves) on hydrology, currents, biogeochemistry and sedimentary dynamics. During the period 2009-2021, the station was located 2,5km away from the river (43.1913°N, 4.5197°E), where the averaged water depth evolved from 20 to 17m depth. Near real-time data were acquired every 30 minutes for most of them and transmitted to the Coriolis data Center to support operational oceanography and facilitate maintenance. Near real-time qualified data are provided, together with post-processed data of velocity and waves from the ADCP. Raw delayed time hydrology data (from Hydrocat and Wisens CTDs) are also provided. The MesuRho station is a component of the national high frequency coastal observing network COAST-HF (http://www.coast-hf.fr) from the ILICO research infrastructure (http://www.ir-ilico.fr) and of the Rhône Sediment Observatory (OSR). Near real-time data can be displayed and downloaded from the website: https://www.coriolis-cotier.org/.