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Membrane perturbation and permeabilization by the lysosomotropic detergent MSDH
Lysosomes are subcellular organelles with acidic interiors (pH 3.5-5), containing enzymes that break down macromolecules and intracellular waste. Controlled release of lysosomal... -
Investigation of the solution structure and pore dynamics of Bacillus anthrac...
Understanding the nature of protein translocating events through bacterial pores offers an uniqueopportunity to develop novel drug delivery systems, whilst also providing... -
Unlocking Structure-Property Relationships in Composite Semiconducting Nanopa...
Colloidal dispersions of organic semiconducting nanoparticles (NPs) have shown promise for the generation of active layers in organic solar cells.Composite NPs containing a... -
On the structure and composition of non-lamellar lipid-based liquid crystalli...
Liquid crystalline particles consisting of glycerol dioleate (GDO) / soy phosphatidylcholine (SPC) mixture and stabilised by polysorbate 80 (P80) have proven to be suitable as... -
Structure and gelation in PVDF-based polymer systems for Li-ion battery appli...
Lithium ion batteries are the power source of choice for portable electrical devices owing to performance in terms of high specific capacity and reliability. Liquid electrolyte... -
Structural characterisation of a transmembrane biological electron conduit us...
Many bacteria are able to respire using solid minerals and metals as electron acceptors in the absence of oxygen or other diffusible substrates. In Shewanella oneidensis this... -
Constructing analogues of Gemini and oligomeric surfactants using polyamines
Gemini or oligomeric surfactants, where two or more alkyl chains and headgroups are connected via spacer groups, have interesting and potentially important properties which make... -
Structural studies of Staufen1 in complex with Upf1, a crucial assembly in ge...
Gene expression is regulated during both the synthesis and the decay of mRNAs. Various pathways of cytoplasmic mRNA decay exist. These include ARE-mediated decay, miRNA-Mediated...