62 datasets found

Ever-more stringent environmental regulations have driven the automotive industry to continuously develop lightweight solutions in automotive body sheet materials, without...

This proposal focuses on a new approach to the formation of rod-like micelles in supercritical CO2 (scCO2). Recent successful high-pressure SANS (HP-SANS) results have shown for...

Mucoadhesion is the ability of polymers to adhere to mucosal membranes in the human body and provide a temporary retention. It has been widely used to develop polymeric dosage...

The pressuriser is a vital part of a pressurised water reactor (PWR). We are now investigating a weld of a pressuriser that has been in operation for 29 years. The long time at...

We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the...

The objective is to refine current understanding about the mechanism of hydrotropy with respect to polarity and electrostatic character of hydrotropes and hydrophobic solutes...

Associative polymers have a very important role as rheological modifiers, due to their ability to form interconnected networks of hydrophobic domains. Additionally,...

Nanogranular thin films of FexM100-x (M=Au,Ag; x=7,20,39) are an excellent system to study the magnetism of nanoparticles in diamagnetic matrices coupled by direct, RKKY and...

This proposal is to probe the gel structure with High Pressure SANS (HP-SANS) using an in-line pressure cell. The ability to control the properties of supercritical CO2,...

Protection of biological molecules during freezing and lyophilisation is of commercial importance to the pharmaceutical, medical, and food industries. Sugars and surfactants...

In recent years much progress has been made in the design of surfactants that are soluble in liquid CO2; hence these additives able to modify physicochemical properties...

Asymmetry across biological membranes is vital for a wide range of organelle and cellular functions. Significant differences in lipid composition have been found between the...

This proposal aims to explore a cheaper and more environmental-benign surfactants for microemulsion formation in CO2; in other words, a low fluorine containing...

The life of modern power generating plant is limited by the high temperature performance of the materials from which it is constructed. The drive for longer operating lives, and...

In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock. Although crucial for protecting cells, as with all ion channels, they have the...

The aim is to improve understanding of solution properties and aggregation of hydrotropes and alkyl¿hydrotropes, and the relationship with common surfactants. Although they are...

The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents. The successful development of...

Nanoparticles made of polymers containing fluorine have promising applications since magnetic resonance imaging using fluorinated contrast agents (19F MRI) enables enhanced...

In a one-pot synthesis, we are able to produce spherical gold nanoparticles capped with antibiotics, without the use of other chemicals by using the antibiotic as the reducing...

Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds...