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Raw reads of direct RNA sequencing of Toxoplasma gondii and Arabidopsis thali...
Correct 3prime end processing of mRNAs is regarded as one of the regulatory cornerstones of gene expression. In a parasite that must answer to the high regulatory requirements... -
Toxoplasma gondii mitochondrial sRNAs
Characterization of short RNAs, in particular rRNAs from mitochondria of Toxoplasma gondii. -
Toxoplasma gondii Raw sequence reads
Toxoplasma infects civet hosts:ME49 -
Toxoplasma gondii Transcriptome or Gene expression
Transcriptome analysis of lytic cycle of T.gondii -
Toxoplasma gondii Raw sequence reads
normal ChIP of toxoplasma RH strain -
RNA-seq for bedaquiline treated Toxoplasma gondii tachyzoites
Gene expression profile of Toxoplasma gondii tachyzoites treated with bedaquiline for 20 hours. -
In vivo CRISPR screens for Toxoplasma using endomembrane-nucleus sublibrary i...
We performed in vivo CRISPR screen of Toxoplasma targeting endomembrane and nucleus-related genes to identify in vivo fitness genes in WT and Ifngr1-deficient mice. Overall... -
Nuclear factor AP2X-4 governs the expression of cell cycle and life stage reg...
RNA-seq were performed to compare the transcriptomic differences between KOX-4 strain (ME49?AP2X-4) and its wild type ME49 Overall design: mRNA profiles of KOX-4 strain... -
Timecourse of transcriptional changes upon eIF4E1 depletion in Toxoplasma gondii
The protozoan parasite Toxoplasma gondii causes serious opportunistic disease due to its ability to persist in patients as latent tissue cysts. The molecular mechanisms... -
Chinese 1 (Wh3 and Wh6 ) tachyzoite RNA-seq
Chinese1, the predominant lineages of T. gondii in China, has large phenotypic differences within the lineages.Global genomic expression analysis of transcripts between WH3 and... -
RNA sequencing of host transcriptome of human foreskin fibroblast cells infec...
The purpose of this data set is to determine if bradyzoites impact the host transcripton in a similar manner as tachyzoites. We found that 3853 differentially expressed genes... -
The transcriptome data analysis of DiCre strain and DiCre Delta SBPase Delta ...
To compare the gene expression difference between DiCre strain and DiCre Delta SBPase Delta TAL strain -
Study of the cytotoxic effect of Cas9 expression in Toxoplasma gondii
Streptococcus pyogenes Cas9 has been widely adopted for genome engineering in a variety of experimental systems, and many promising therapeutic applications. Understanding the... -
Functional screening prioritizes apicomplexan cysteines for covalent drug dis...
Nucleophilic amino acids are important in covalent drug development yet underutilized as antimicrobial targets. Chemoproteomic technologies have been developed to mine... -
Population Genomics for Far-East Asian Toxoplasma gondii
Toxoplasma gondii is a global protozoan pathogen. Clonal strains predominate in Europe, North America, Africa, and China, while highly recombinant parasites are prevalent in... -
Inactivation of phosphate transporters alters gene expression in T. gondii
Purpose:This study was aimed to profile the transcriptome changes of Toxoplasma after loss of phosphate transporters. For this purpose, phosphate transporter TgPiT and TgPT2... -
Effect of BFD2 (TGME49_311100) deletion on gene expression in Toxoplasma gondii
The acute-to-chronic stage transition in Toxoplasma gondii involes a global restructuring of the parasite transcriptome and is induced under alkaline stress. We found that... -
ChIP-seq data analysis of TgAP2XII-1 on the whole genome of Toxoplasma gondii...
Transcriptomic analyses revealed the gene expression changes after AP2XII-1 depletion. To see which of these differentially expressed genes are directly targeted by AP2XII-1, we... -
Transcriptome sequencing of WT and chloroquine resistance transporter (TgCRT)...
Purpose: TgCRT spans the membrane of the digestive vacuole of Toxoplasma parasites. The deletion of TgCRT causes the swelling of the digestive vacuole, which could interfere... -
Toxoplasma gondii Infection Induces Ferroptosis in vivo and in vitro
Toxoplasma gondii is an obligate intracellular protozoan parasite which seriously threatens the health of domestic animals and humans. However, its association with ferroptosis...