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Elucidating the unique role of non-standard collagen helices in forming key p...
The collagens are the most abundant proteins in mammalian systems, comprising up to 25% of human proteins. Their three-stranded triple helix structures are a major determinant... -
Polyelectrolyte surfactant complexes
Approved proposal under the ICRD Scheme Proposal ICRD0005 -
Dynamic ferromagnetic domains in a frustrated 1-d chain system
We propose to carry out a small angle scattering experiment on LOQ or SANS2D on a frustrated Ising chain system. SrHoCrO6 is based on ferromagnetic chains arranged on a... -
Small angle neutron scattering experiment of a novel pH and temperature sensi...
The aim of the present study is to investigate the effect of different stimuli on a novel iron oxide core shell nanoparticles. The system is composed of a magnetite core with a... -
Solubilisation in Zwitterionic Micelles: Effect of Structure
The project aims to probe the relationship between surfactant structure, the micelles formed in solution, and the type of drug molecules that the micelles solubilise. Once... -
Encapsulation of Non-Steroidal Anti-Inflammatory Drugs Using Novel Pluronic G...
The research topic is encapsulation of a hydrophobic drug, flurbiprofen, using novel amphiphilic graft copolymers (AGCs). The AGCs of interest are shown in Figure 1: Preliminary... -
DNA unwinding mechanism of the archaeal helicase PabMCM
The process of cell division requires precise duplication of the genetic material. The separation of the two strands of DNA and the progression of the replisome are driven by... -
Encapsulation of monomers in cationic surfactant-polymer solutions
We have been studying the solution interactions leading to formation of solid polymer-surfactant films at the air-solution interface. We wish to use the mesostructures in the... -
SANS Contrast Matching Studies of Radiation-grafted Anion-exchange Membranes
We request two days beam time on SANS2D for the study of radiation-grafted anion-exchange membranes, both dry and hydrated under different ratios of D2O/H2O. These materials... -
Kinetics of amphotericin B interaction with model human and fungal cell membr...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents. The successful development of... -
SANS study of effect of water soluble polymers on aggregation behaviour of co...
Aggregates of the cationic conjugated polyelectrolyte (CPE) HTMA-PFP with poly(vinyl alcohol) (PVA) will be studied in aqueous solutions using SANS. Previous fluorescence,... -
Selective adsorption of polymer on Janus particles
Janus particles, bearing two distinct compositions on the surface of the same particle, have attracted much attention recently as a way to finely tune morphology and... -
Micellization in glycerol:choline chloride deep eutectic solvent
Deep Eutectic Solvents (DES) are molecular mixtures with melting points below room temperature. DES share many features of ionic liquids (low vapour pressure, adjustable... -
Structure-function studies of Replication Protein A, a crucial player in geno...
Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds... -
Conformations in partially mixed block copolymers of partially deuterated pol...
Nascent 'disentangled' block copolymers of Ultra-high Molecular Weight Polyethylene (UHMWPE) with a reduced number of entanglements were synthesized having protonated (hPE) and... -
pH responsive Core-Shell-Corona (CSC) micellar complexes: Corona- and teleche...
Coacervation is an electrostatically-driven liquid-liquid phase separation process, resulting from the association of oppositely charged macro-ions. In this framework,... -
Formulating polymer solutions to stabilise polymeric foams
Polyurethane foams (PUF) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agents... -
Cellulose-based polyelectrolytes for microencapsulation: conformational trans...
Addition of multivalent salts to water soluble polyelectrolytes, such as sodium carboxymethyl cellulose (NaCMC), induces conformational change to the polyelectrolyte structure,... -
NTC 2018 Proposal Example 1
Please ignore. This is just for setting up ERAs ready for the Neutron Training Course. -
Self-assembling behaviour of N-acyl amino acid-based surfactants
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered...