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Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
Neutron reflectivity studies of the interaction of amphotericin with model ce...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
NR study of binding of short antimicrobial alpha-helix peptides with model li...
In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,... -
Adsorption of sodium polyacrylate to sapphire - how does a colloidal stabiliz...
Stabilizers of colloidal particles are often complex and their function may involve several mechanisms to impart stability of a wide range of conditions. Sodium polyacrylate is... -
Interaction of Chiral Amino Acids with Hydrated Vermiculite Clay
The aim of this proposal is to obtain an atomistic understanding of the adsorption of chiral amino acids on mineral surfaces. Our previous experiments on LOQ and at ILL on D16... -
How does oxidative damage change peptide membrane insertion?
The insertion of peptides and proteins into cell membranes is crucial for the functioning of cells, and also for the functioning of a variety of antibacterial reagents. Cells... -
Effect of electrochemical control function and dopant anion on polyaniline fi...
We propose to determine the structures (polymer and solvent populations and spatial distributions) of polyaniline films deposited by different protocols. These involve different... -
The Orientation and Conformation of Synthetic 3-10 Helical Peptides within Su...
This dataset has no description
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NR study of binding of short antimicrobial alpha-helix peptides with model li...
In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,... -
Adsorption of Sodium Bis-(2-ethylhexyl)phosphate on a-Alumina
In this proposal we investigate the adsorption of a key additive and functional group used in lubrication and wear applications using neutron reflection on a metal oxide... -
Understanding the evolution of a magnetic soliton after nucleation 3d magneti...
The aim of this proposal is to understand the initial propagation of a sharp magnetic soliton after nucleation in tall synthetic ferrimagnetic structures (with six and eight... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
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Interaction of amino acid based biosurfactants with model lipid bilayers
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered... -
Packing structural conformation of (H/D) nanogels at the air/water interface
The interfacial behaviour of thermoresponsive N-propylacrylamide (NPAM) based nanogels differs from solid nanoparticles because of the soft structural character. These nanogels... -
A study of hole injection efficiency for a model conjugated bilayer system
Polymer-based electronics have attracted huge interest due to their wide applicability to light emitting diodes, field effect transistors and photovoltaics. The aim of our... -
Probing membrane localisation of molecular rotors
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Adsorption of Monoclonal Antibodies at the Solid/liquid Interface
We propose to use neutron reflection to study the interfacial adsorption of 2 novel bispecific therapeutic antibodies at the silicon oxide/water interface. To enpower each of... -
Formation of asymmetric free-standing bilayers with lipopolysaccharide in the...
We have recently improved the stability and coverage of free standing bilayers by the use of a supporting thiolipid layer on gold. The system has been investigated on POLREF and... -
Detailed Structure of Phospholipid Bilayers from Multiple Contrast Neutron Re...
In recent monolayer measurements, we have developed models for obtaining detailed structural information of phospholipid structures. The models employ a 'quasimolecular'... -
Adsorption of perfluoroalkyl substances to solid soil interface to elucidate ...
Perfluoroalkyl substances (PFASs) are stable compounds and commercially desirable. They are widely used, for example, as surfactants in textile and paper products and in aqueous...