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Magnetic Ground State of a New Honeycomb Iridate
A new layered iridate material, Cu2IrO3, has been fabricated. This material is isostructural with the much-studied Na2IrO3 and has a nearly ideal honeycomb structure that should... -
Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier... -
Probing membrane localisation of molecular rotors (SANS)
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Structural characterization of a series of polymer-protein conjugates for chr...
Polymer-protein conjugates have been designed to deliver an appropriate target growth factor to promote a more rapid healing of chronic wounds, an incredibly important area for... -
Phase Separation in Organic Photovoltaic Cells
Organic photovoltaic (OPV) cells have the potential to be the basis of a renewable energy source that is inexpensive and portable. Current state-of-the-art solution-processed... -
SANS Study of the interaction of model wax alcohols with non-ionic surfactant...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
Unraveling the structural ordering of water in amorphous calcium carbonate (A...
Carbonates and phosphates are highly important in biomineralization. They are found as hydroxyapatite (Ca5(PO4)3OH) in bone or calcite/aragonite(CaCO3) in seashells and... -
Investigating a Dextrin-Phospholipase A2 Conjugate as a Trigger for Polymer E...
Recent research has demonstrated the potential of nanosized delivery systems for routine use in many diseases, eg cancer, viral diseases and rheumatoid arthritis [1,2], due to... -
SANS contrast measurements on important protein/DNA interactions from RCaH
This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing... -
Structure-function studies of Replication Protein A and its complexes with DNA.
Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds... -
Interaction of a pH-sensitive Polymer with a Model Lipid Membrane in the Form...
This SANS experiment was proposed by 4 PhD students from 3 different institutions in a Marie-Curie Training Network. They are all in the second year of their PhD and their... -
Encapsulation of hydrophobic species in mixed micelles in polymer solutions
This proposal continues our investigations into film-forming polyelectrolyte-surfactant solutions. We have found that mixed micelle systems offer greater control over micelle... -
Self-assembly of detergent molecules below ambient temperature: SANS to deter...
Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we... -
Commissioning of a new continuously-loaded high-pressure piston-cylinder cell
We request two days on Engin-X to carry out commissioning tests on a pair of new piston-cylinder cells and their associated hydraulic press. Although intended primarily for use... -
Contrast variation SANS to understand drug directed assembly of multi lamella...
Recurring infection following dental interventions such as fillings is the most common reason for failure, leading to further treatments including root canal therapy, where the... -
Unraveling the structural ordering of water in amorphous calcium carbonate us...
Calcium carbonates make up some of the most abundant minerals in the world. They are of great importance in geology and in the field of biomaterials as well as having several... -
Detailed structures of surfactant micelles
Measurements are required for Sans2d resolution checks and also the overlap of the two Sans2d detectors. Proposal submitted to panel and they deemed it should be done as... -
Single Crystal Scattering Study of 163-Dy2Ti2O7 Using SXD
Spin ice materials are a class of compounds with exotic magnetic properties, resulting from the frustration. Magnetic monopoles have been detected at low temperature; manifest... -
Short peptide self-assembly and pesticide solubilisation in binary surfactant...
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