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Engineering nanoparticles for protein therapeutics - quantifying membrane acc...
The self-assembly properties of lipid systems can be exploited to form lipid membranes with complex morphologies. These include membranes with a lattice-type internal structure... -
Solution aggregation of short peptide surfactants
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
Structure determination of solution aggregation of single alkyl chain PC surf...
We have synthesised alkyl phosphorylcholine (CnPC) surfactants in hydrogenated and deuterated form and have determined their solution aggregation using SANS. In this part of... -
Refining compositions for bio-active phosphate glasses
We wish to investigate the structural changes which arise when B2O3 is added to a bioactive phosphate glass. We are particularly interested to study the phosphate environment... -
Understanding the microstructure of polymer blends used as control release co...
Solid oral dosage forms consist of polymer layer encapsulated drug-bound particles with a desired drug release profile e.g. pulsatile, controlled, delayed and targeted,... -
Structural Studies of High Level Waste Glass
The aim of this proposal is to develop a methodology to investigate multicomponent glass structure, combining neutron diffraction, XRD, NMR, ab initio MD, and RMC. We wish to... -
Quantitative analysis of precipitate coarsening in V and V-Mo microalloyed steel
Ever-more stringent environmental regulations have driven the automotive industry to continuously develop lightweight solutions in automotive body sheet materials, without... -
The effect of interface roughness on proximity induced magnetisation and inte...
Interface effects, including proximity induced magnetisation (PIM), play an import role in many spintronic devices employing heavy metal/ferromagnetic structures. Interface... -
Solution aggregation of lipopeptides: SANS structure determination
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Effect of alloying on the misfit of Ni-Ni3Al-Ni3V alloys
The exceptional high temperature mechanical properties of Ni-base superalloys has resulted in their widespread use in high temperature applications. These alloys conventionally... -
Monitoring the structural transition of a hydrophobic amphiphile from the iso...
We propose a SANS experiment to investigate a structural transition involving an alkylated fullerene-C60 (an alkyl-aromatic hydrophobic amphiphile) in alkane solvents from an... -
Co-surfactancy of oil-soluble and water-soluble surfactants in emulsion stabi...
The structures of emulsions formed from mixed oil-soluble and water-soluble amphiphiles (respectively derivatives of polyisobutylene, PIBSA, and polyacrylamide, PAM) will be... -
A study of hole injection efficiency for a model conjugated bilayer system
Polymer-based electronics have attracted huge interest due to their wide applicability to light emitting diodes, field effect transistors and photovoltaics. The aim of our... -
The application of INS to examine high specification Fe Fischer-Tropsch catal...
Over the last 4-5 years the research team have been developing INS methodology that can be applied to investigate Fe Fischer-Tropsch (F-T) catalysts. The first stage of that... -
Effect of End Group on RAFT-Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Compatibilisation of polymer blends using electrospinning
This proposal seachs time to establish the conditions under which electrospinning can be used to provide (non-equilibrium) mixtures of immiscible polymers. Such an outcome might... -
SANS Study of the interaction of reconstituted model wheat waxes with non-ion...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Superstructures in insulating and metallic lanthanum-doped sodium cobaltate
The thermoelectric properties of NaxCoO2 can be substantially improved by replacing Na ions by cations of higher valence. Our neutron diffraction studies on SXD for doping with...