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Pol II pausing is a milestone on the road to complex animals
PRO-seq experiments in multiple organisms. Also, PRO-seq experiment of Nelfb and Nelfe degron mESC in serum/LIF with or without dTAG-13. Overall design: We used Precision... -
Tracking the origin and evolutionary dynamics of RNA editing in metazoans
Whole-genome DNA-seq and strand-specific RNA-seq on 18 species, including 14 metazoans and four unicellular eukaryotes closely related to metazoans. For each species, two to... -
Sequencing short capped RNAs captures acute transcription initiation and iden...
The spatial and temporal regulation of transcription initiation is pivotal for controlling gene expression. Here, we introduce capped-small RNA-seq (csRNA-seq), which uses total...