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20Mammals
Definition of functional regulatory regions in the vast non-coding fractions of mammalian genomes remains a daunting challenge that underscores our limited understanding of... -
RNA-Seq analysis of gene expression divergence in mammalian liver
The connection between evolution of regulatory elements and downstream gene expression is incompletely understood in mammals. We carried out a large-scale comparison of matched... -
Mitochondrial heteroplasmy in vertebrates using ChIP-sequencing data
Mitochondrial heteroplasmy, the presence of more than one mtDNA variant in a cell or individual is not as uncommon as previously thought. It is mostly due to the high mutation... -
dsRNA-Seq: Identification of viral infection by purifying and sequencing dsRNA
RNA viruses are a major source of emerging and re-emerging infectious diseases around the world. We developed a method to identify RNA viruses that is based on the fact that all...