19 datasets found

This proposal addresses bilayer swelling experiements on floating supported bilayers (FSBs) in the presence of biological buffers. Previous work on multilamellar vesicles has...

The aim of the present neutron reflectivity proposal is to obtain stereochemical and kinetic information studying the thermo-lyotropic behaviour of the lipid mixture DOPC-DDAB...

An eggshell membrane polypeptide is highly surface active and effective at emulsion stabilization. We explore how to use SANS to study the interfacial layers surrounding the...

Despite the increasing use of nanoparticles (NPs), our current knowledge of how NPs interact with the human body or the environment remains limited. Of a number of mechanisms, a...

This proposals aims to investigate the atomic and intermediate range structure in model membrane environments. By beginning with a disperse system of a phosphocholine lipid in...

The mechanism of action of inhalation anaesthetics such as N2O and the inert gases are unclear. Direct binding to receptor sites on membranes would rely on weak intermolecular...

Mineral aerosol in the atmosphere is a major part of the Earth’s aerosol budget. Organic films on these aerosols affect the aerosol’s ability to promote cloud formation and...

Surfactants are frequently used in personal care products to improve the wetting and oil solubilizing qualities of the products, which also leads to the skin irritation by...

Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment....

Nitrous oxide, N2O, is an inhalant anaesthetic with a long history of use dating back to 1844. It is most commonly used as a light sedative in dentistry, or in child birth and...

We propose to investigate the role of lateral phase separation on LPS insertion into model membranes and the effects of target membrane structure and composition. A comparison...

Surfactants have been widely used in cosmetics, detergents and pharmaceutical industries. These applications are always accompanied by surfactant-induced skin irritation which...

The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers...

A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We...

In a proof-of-concept beamtime award (RB1220486) we studied the process of platinum-catalysed benzene hydrogenation in the pores of MCM-41 using standard neutron diffraction...

The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface....

The oxidative processing of pollutants in Polar clouds affects droplet size and optical properties. Polar clouds contain naturally occurring organic lipids forming organic films...

The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with...

As research on apoptosis has gained momentum, the importance of membrane lipids in this crucial cellular process is becoming clear.Previously, we have determined using NR and...