25 datasets found

We have a programme investigating the structure and function of protein scaffolds oriented on gold surfaces using sulfur chemistry for attachment. The aim is to direct the...

Bilayers which float below a self-assembled monolayer (SAM) coated solid support represent one of the most advanced membrane mimetics. Recently (RB 1720155) we assessed the...

Copper (I) hydride, CuH, is unique amongst the binary metal hydrides in that it can be synthesised, at room temperature, in aqueous solution. In recent years CuH generated in...

A proposal is made to continue ongoing ALC-muSR experiments on the green-tea anti-oxidant EGCG and its analogue. Several overlapping resonances observed on HiFi made it...

As part of a facility project aimed at developing a new sample environment allowing simultaneous in-situ neutron diffraction and Raman spectroscopy, we propose to study the...

Oxidation of lipid membranes is widely known to play a crucial role in many cellular processes and pathological conditions such as apoptosis, inflammation, infection, or sepsis,...

A surfactant-free microemulsion is ternary system consisting of two completely miscible molecular liquids and a third one that is only highly soluble in or miscible with one of...

Silicon-doped aluminophosphates (SAPOs) are framework materials similar to zeolites. Their pore structure and solid acid sites contribute to their activity and selectivity in...

The aim of the present proposal is to investigate the mechanism of CO oxidation over hydrous palladium oxide, both directly and indirectly. For the direct route, the sample will...

The outer membrane of Gram negative bacterial is an effective barrier for many harmful agents. We have been developing and testing advanced models of the Gram negative bacterial...

Our ongoing project to characterise radical scavenging by the green tea anti-oxidant EGCG and its D-ring analogue, (3,4,5-(OH)3-Bz) is near-complete. ALC-MuSR experiments on the...

We propose to characterise selected radical structures of the green-tea anti-oxidant flavenoid EGCG (& selected analogues), by DFT/post-HF computation and ALC-MuSR, towards...

Atherosclerosis is the leading cause of death in western society, its consequences such as strokes and heart attacks arise from the build-up of plaques of fat which accumulate...

The formation of silk fibres in both spiders and silkworms is characterized by a conversion of short range ordered structures in solution into long range ordered beta-sheet rich...

Perfluoroalkyl substances (PFASs) are fully fluorinated, stabile, and surface-active compounds. They contain both a hydrophobic fluorinated carbon chain and an ionizable...

Composites materials that combine the flexibility and mechanical robustness offered by polymers with the functionality displayed by metal oxide nanoparticles offer new insight...

Recently we have been investigating the mineralization of polymer-surfactant films to create thicker and more robust self-supporting membranes. Our previous experiments used the...

Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer...

We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This...

In this proposal we wish to continue our current work on mesostructured inorganic films in largely ethanolic solutions, containing limited amounts of water. Transition metal...