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Sneek Kleinzand 17 Waarderend booronderzoek
In opdracht van de gemeente Súdwest-Fryslân heeft Salisbury Archeologie b.v. in samenwerking met ArcheoSupport b.v. een bureauonderzoek gevolgd door een waarderend booronderzoek... -
Molecular architecture of novel, trichain-containing vectors for gene delivery
We have recently developed novel ternary lipopolyplex vectors (i.e. gene delivery vectors containing cationic lipid, plasmid DNA and a cationic peptide) in which, for the first... -
Folated derivatized nanoemulsions for the treatment of cancer
Nanoemulsions (NE) i.e. nanoparticles containing a fluid lipid or oil dispersed in water and stabilized by a surfactant particles have attracted considerable attention as... -
Effect of serum on the structure of gene delivery vehicles
To date complexes prepared from vesicles composed of dichain, cationic lipids (L) with negatively charged DNA (D), known as LD complexes have emerged as one of the major... -
Microdomains in model membranes using contrast variation SANS
In the present proposal small angle neutron scattering will be used in combination with contrast variation as a non-invasive method to detect the presence and size formation of... -
Effect of surfactant head group on micelle structure of drug containing micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms... -
Changes of phospholipid aggregate morphology induced by phospholipase hydrolysis
We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the... -
Probing the internal structure of gene delivery vehicles using contrast varia...
Gene delivery vehicles, known as LPD complexes, prepared from mixing cationic lipid vesicles (L) with cationic peptide (P) and DNA (D) have proven to be very effective at... -
Microemulsion formulations for local anaesthesia
Although microemulsions have been investigated as potential drug delivery vehicles, little work has been performed establishing the detailed molecular architecture of the... -
Structure of oil-in-water microemulsions containing eutectic mixtures of ment...
Although microemulsions have been widely investigated as potential drug delivery vehicles, relatively little work has been performed establishing the detailed molecular...
