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20Mammals
Definition of functional regulatory regions in the vast non-coding fractions of mammalian genomes remains a daunting challenge that underscores our limited understanding of... -
Evolution of CpH methylation in vertebrate brains
The brain requires complex mechanisms of genome regulation to encode and store behavioural information. In mammals, DNA methylation deposited at non-CG dinucleotides... -
RNA-Seq analysis of gene expression divergence in mammalian liver
The connection between evolution of regulatory elements and downstream gene expression is incompletely understood in mammals. We carried out a large-scale comparison of matched... -
Mitochondrial heteroplasmy in vertebrates using ChIP-sequencing data
Mitochondrial heteroplasmy, the presence of more than one mtDNA variant in a cell or individual is not as uncommon as previously thought. It is mostly due to the high mutation... -
Transcriptomic evolution across bilaterian tissues
We investigate tissue transcriptomic evolution across bilaterian animals by analyzing RNA-seq data from eight different tissues across twenty species. Overall design:... -
DNA Zoo
The DNA Zoo is a consortium focused on facilitating conservation efforts through the rapid generation and release of high-quality genomics resources. -
Germline mutation rate in vertebrates
We estimated the germline mutation rate of 68 species of vertebrates using WGS of pedigrees (i.e. at least 3 individuals mother, father, and their offspring).
