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SANS Studies of Novel Internally Stabilised Liposomes
Internally supported liposomes (ISLs) are composed of polymeric spheres enclosed by liposomes. Although very little research has been done on ISLs, understanding their... -
Adsorption Structures of Organics additives at the Iron/Oil Interface and the...
Numerous chemical additives have been added to steel surfaces to improve adhesion, and prohibit corrosion if the substrate is reactive to its surrounding environs. This... -
Zwitterion doped PEDOT:PSS bulk morphology modification as a function of dopi...
We propose to use SANS to study the intra-particle information (size, shape, interactions) of pristine and zwitterion doped PEDOT:PSS in order to have a better understanding of... -
Folated derivatized nanoemulsions for the treatment of cancer
Nanoemulsions (NE) i.e. nanoparticles containing a fluid lipid or oil dispersed in water and stabilized by a surfactant particles have attracted considerable attention as... -
Oxidative stress and lipid membrane disruption in bilayers containing polyuns...
Oxidation of lipid membranes is widely known to play a crucial role in many cellular processes and pathological conditions such as apoptosis, inflammation, infection, or sepsis,... -
Nanosuspsomicroemulsions: nanosuspension stabilty
At Kings College London we have recently developed a novel combination formulation, a nanosuspsomicroemulsion (NSME), comprising of a microemulsion (ME) containing one drug and... -
Introducing the O-antigen in Bacterial Outer Membrane in vitro Models Pt. III...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Investigating the internal structure of thermally annealed two-component poly...
The elucidation of the compositional profile of polymer:small molecule nanoparticle films is critical for applications such as water processable organic solar cells. In order to... -
Effect of oxidative stress on polyunsaturated lipid bilayers modulated by cho...
The exposure of biological membranes to reactive oxygen species is key for many pathological conditions, including inflammation, infection, or sepsis. Lipid peroxidation is... -
Mapping of micro-strain and macro-strain evolution by shot, laser-shock, and ...
Peening is a surface treatment method to improve the fatigue life of engineering components. Recent development of peening technique such as laser-shock and cavitation shotless... -
How do colloidal nanocrystals appear to biological systems? A SANS study of t...
A key aspect of any biological application of nanomaterials is to understand what happens when they are introduced into biological environments. When particles are introduced... -
Co-assembly of gold nanoparticles with wormlike micelles
Gold nanoparticles (GNPs) are attracting tremendous interest in nanotechnology due to their plasmonic properties, in particular the localized surface plasmon resonance effect... -
Neutron reflection from nanoparticles interacting with insoluble monolayers
Cell-nanoparticle interactions are complex, involving several specific and non-specific intermolecular forces between a wide range of particulate and molecular species . There... -
Interfacial structures and competitive adsorption of amphiphilic polymers wit...
Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and... -
Neutron reflection studies on model wax films reconstituted from chemicals
Morphological features of plant waxes vary from species to species, but little is understood about what controls these morphological changes although it is widely believed that... -
Nanoparticle-surfactant layers at the water-oil interface
The spontaneous selfassembly of nanoparticles (NP) at liquid-liquid interfaces is a phenomenon present in nature and relevant for many applications, such as, emulsion... -
Investigating the Influence of Polymer Properties on Cyclic Peptide-Polymer C...
Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes (CPNTs). The conjugation of polymers to these peptides renders the... -
A Study of AuMu^+ Final States by Dia RF Resonance
Small-sized metal nanoparticles (NPs) are of long standing interest to both magnetism and heterogeneous catalysis. Recent muSR studies of Au NPs encapsulated in mesoporous... -
Microemulsion formulations for local anaesthesia
Although microemulsions have been investigated as potential drug delivery vehicles, little work has been performed establishing the detailed molecular architecture of the... -
Membrane interactions of virus-like silica nanoparticles as antimicrobial pep...
As a result of an increasing number of bacteria developing resistance against antibiotics, antimicrobial peptides (AMPs) are currently attracting significant interest. However,...