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Lateral Phase Behavior in bulk heterojunction films containing low-molecular ...
Grazing incidence small angle neutron scattering (GISANS) will be used to investigate the lateral phase behavior in thin films of blends of electron-donor... -
Effect of lipid oxidation on raft formation using contrast variation SANS
The very heterogeneous, but non-random, arrangement of lipids and proteins in cell membranes are of major scientific interest and led Simons and Ikonen to propose that ¿rafts,¿... -
Competetive adsorption at the oil-water interface protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Investigating liposome sensitivity towards phospholipases for applications in...
Liposomes are lipid-based, water-filled vesicles with wide-ranging applications in diagnostics and drug delivery. Phospholipases (PLs) are enzymes that cleave specific bonds in... -
Solvation of cellulose-derivate polyelectrolyte in mixed solvents and added s...
Carboxymethylcellulose (NaCMC) is the most widely used cellulose derivative; it forms an anionic, water-soluble, polyelectrolyte with vast applications in the food,... -
Mechanism and rates of phospholipid exchange and flip-flop under physiologica...
Variation in lipid composition between different biological membrane and across membranes are vital for a wide range of cellular functions. Significant differences in lipid... -
Microdomains in model membranes using contrast variation SANS
In the present proposal small angle neutron scattering will be used in combination with contrast variation as a non-invasive method to detect the presence and size formation of... -
Effect of oxidation on lipid raft formation: a SANS study
The separation of particular lipids in cell membranes into liquid ordered and liquid disorder regions is thought to have a major influence of the functioning of membrane... -
Kinetic studies of the Trost ligand particpating in a catalytic cycle
The aim is use time-resolved SANS to monitor the changes in aggregation structure of the Trost ligand[1] Pd-catalyst [(DACH-phenyl-TSL)Pd+(η3-C6H9)]BArF- 1 (Figure 1 left)... -
Solution structures of three immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Protein interactions at solid-liquid interfaces: The effect of affinity colum...
Biopharmaceuticals are manufactured using chromatographic procedures including adsorption and desorption processes at the solid-liquid interface. These events take place in... -
Micelle formation from model surfactant binary and ternary compositions in th...
The effects of electrolytes on SLES3, C12E8 and LAS4 has been extensively studied, especially the effect on the critical micelle concentration of each surfactant. We wish to... -
Conformations in partially mixed block copolymers of partially deuterated pol...
Nascent 'disentangled' block copolymers of Ultra-high Molecular Weight Polyethylene (UHMWPE) with a reduced number of entanglements were synthesized having protonated (hPE) and... -
The competition between two polymers for adsorption onto one surface
The behaviour of multiple polymers in competition for colloidal silica has previously been investigated in our group using solvent relaxation nuclear magnetic resonance. We... -
Structure of siRNA containing delivery vehicles: effect of serum
Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR... -
Self-assembly of nonionic surfactant in alcohol/water from room temperature t...
Surfactant self-assembly has been extensively studied in aqueous solution at room temperature or above, but it was less documented at temperatures below 0 °C. Our preliminary... -
Reconstituted lipoprotein particles - Implications of structure and dynamics ...
Neutron scattering will allow to advance the understanding of lipoprotein behavior in solution and at the interface of relevant biological interfaces. Here we focus on HDL... -
A SANS Study of Hierarchical Order in DNA Complexes with Trojan Peptides
We will use SANS to investigate the nanoscopic structure i.e., sizes in the range 2-200 nm of complexes formed by cell-penetrating peptides and nucleic acid species. The... -
Solution structures of the immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Control of oil exchange dynamics in microemulsions by amphiphilic copolymers
A very important property of O/W microemulsions is the exchange dynamics of the oil molecules. So far little is know about that, despite the fact that its control is crucial for...