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Extrachromosomal circular DNA is common in yeast.
Examples of extrachromosomal circular DNAs (eccDNAs) are found in many organisms but their impact on genetic variation at the genome scale has not been investigated. We mapped... -
Evolutionary and reverse engineering of single vitamin requirement in Sacchar...
The popular Saccharomyces cerevisiae laboratory strain CEN.PK113-7D is regularly grown in chemically defined also referred to synthetic media (SM) that contain, a set of organic... -
Saccharomyces cerevisiae CEN.PK113-7D Genome sequencing
Genome analysis of evolutionary engineered n-butanol-tolerant yeast strains. -
Anaerobically evolved fungi that harbor Class II dihydroorotate dehydrogenase...
The goal of this study was elucidate the respiratory chain dependency of the abovementioned Class II DHODs. The URA9 genes of Anaeromyces robustus, Sch. japonicus, D.... -
Saccharomyces cerevisiae CEN.PK113-7D Raw sequence reads
In this study, we investigated the improved glycerol growth phenotype of CEN.PK strains evolved for improved growth in synthetic glycerol medium and successfully identified two... -
Characterization and laboratory evolution of mRNA-sized RNA import in mitocho...
Although editing of genomes has been revolutionized since the development of the CRISPR/Cas9 technology, even the most genetically accessible eukaryotes harbor a genome that is... -
Arginine auxotrophy by deletion of the mitochondrial selectable marker ARG8 i...
Mitochondria are essential organelles due to their role in oxidative phosphorylation and biosynthesis of essential molecules. Saccharomyces cerevisiae is a popular model... -
Laboratory evolution of a biotin-requiring Saccharomyces cerevisiae strain fo...
Biotin prototrophy is a rare, incompletely understood and industrially relevant characteristic of Saccharomyces cerevisiae strains. The genome of the haploid laboratory strain...
