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Folated derivatized nanoemulsions for the treatment of cancer
Nanoemulsions (NE) i.e. nanoparticles containing a fluid lipid or oil dispersed in water and stabilized by a surfactant particles have attracted considerable attention as... -
Nanosuspsomicroemulsions: nanosuspension stabilty
At Kings College London we have recently developed a novel combination formulation, a nanosuspsomicroemulsion (NSME), comprising of a microemulsion (ME) containing one drug and... -
Effect of surfactant head group on micelle structure of drug containing micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms... -
Location of the lipophilic drug testosterone propionate at the oil-water inte...
Solubilisation of poorly-water soluble drug in surfactant micelles is an attractive means of increasing the apparent aqueous solubility of such drugs in order to administer the... -
Probing the internal structure of ethyl butyrate containing microemulsions us...
The proposal aims to establish the location of the oil, ethyl butyrate in dodecyldimethylamine-N-oxide (DDAO) microemulsions. Molecular dynamic simulations have proposed that a... -
Microemulsion formulations for local anaesthesia
Although microemulsions have been investigated as potential drug delivery vehicles, little work has been performed establishing the detailed molecular architecture of the...