-
Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping
N4-acetylcytidine (ac4C) is an ancient and highly conserved RNA modification, present on tRNA, rRNA and recently investigated in eukaryotic mRNA. We report ac4C-seq, a chemical... -
Gene resolution Hi-C shows Euryarchaeal genomes are folded into SMC-dependent...
Chromosome conformation capture (3C/Hi-C)-based methods probe the average 3D organization of genomes, revealing fundamental aspects of chromosome dynamics. However, when applied... -
Polar membrane lipids and elemental composition of Thermococcus kodakarensis ...
We observed significant changes in the elemental and intact polar lipid (IPL) composition of the archaeon Thermococcus kodakarensis (KOD1) in response to growth stage and...