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Interfacial adsorption of monoclonal antibodies and antigen binding
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Heterogeneous protein exchange at the solid/liquid interface using deuterated...
The formation of protein layers on surfaces is important for medical implants and for the consequences of the ingestion of nanoparticles. In the body, a surface is exposed to a... -
Adsorption of modified polysorbate (Tween) surfactants at the air-water inter...
The nonionic polysorbate (Tween) surfactants are an important class of food grade surfactants. They are extensively use in emulsion and foam stabilisation, and are increasingly... -
Polymer-surfactant films containing glucose sensors
This proposal continues our research on mesostructured surfactant templated polymer films that form spontaneously at the air-water interface. Our recent research has shown it is... -
Manipulating surface multilayer structures in hydrophobin-Tween mixtures
Increased environmental pressures and awareness is promoting a major drive towards an increased use of biosurfactants to produce more biosustainable and biodegradable consumer... -
Understanding and Controlling Biosurfactant self assembly in solution
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
Spontaneous surface multilayer formation in oligoamine ¿ surfactant mixtures
This proposal is part of a major EPSRC (EP/GR065705)/Unilever funded programme to develop and control the spontaneous formation of surfactant multilayer structures at... -
Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
It is difficult for the naked external gene to become internalized due to its similar charge to the extracellular membrane surface. Various cationic copolymers and cationic... -
Microscopic dynamics of water associated to phospholilipd/polysaccharide nano...
In recent years nano- and microparticles composed of polymeric or lipid material have been proposed as drug carriers. Their use allows the modification of the biopharmaceutic... -
Interfacial Adsorbtion from Nematic Mixtures
The aim is to determine the amount of absorbtion of the one component of a mixture at the nemtic/air interface using neutron reflection. The host material in the mixture will be... -
Biosurfactant conventional surfactant mixing. Where nature does it better ?
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
Kinetics of surfactant multilayer formation / dissolution at interfaces
The formation of multilayer structures at surfaces and interfaces from self-assembly in mixed surfactant and in polymer / surfactant mixtures has been recently reported, and... -
Co-adsorption of eggshell membrane polypeptide-surfactant mixtures at oil-in-...
An eggshell membrane polypeptide is highly surface active and effective at emulsion stabilization. We explore how to use SANS to study the interfacial layers surrounding the... -
Neutron reflectivity of self-assembled Janus Nanoparticles
Here we propose to study the Janus character of self-assembled amphiphilic nanoparticles. For that amphiphilic core-shell nanoparticles will be synthesized with a surface... -
Fundamentals of Nanotoxicity: The Role of Nanoparticles in Lowering the Energ...
Despite the increasing use of nanoparticles (NPs), our current knowledge of how NPs interact with the human body or the environment remains limited. Of a number of mechanisms, a... -
Enzyme-catalysed templating of biosilica
Summary. Silicatein in marine sponges catalyses the condensation of silica but the mechanism of layer-by-layer growth of the silica spicule is unknown since sufficient... -
Studying the lateral organisation of mixed phospholipid bilayers by diffuse n...
Off-specular neutron reflection is potentially a powerful technique for studying the lateral organisation of phospholipid bilayers. However, this has not yet been demonstrated.... -
Extreme Synergistic mixing in Biosurfactant ionic surfactant mixtures
The biobased economy growing substantially and pressure to reduce reliance on palm and crude oil derived materials, demand that Home and Personal Care industries develops... -
Effects of confinement on polymeric surfactants
Polymeric stabilisers are often used in the preparation of emulsions and dispersions of particles. The purpose of this additive is to help keep the mixture stable so that it can... -
Multilayer formation at the air-water interface in polyamine / surfactant mix...
The spontaneous formation of multilayer structures at interfaces by surfactant self-assembly is emerging as an important and more common structural signature associated with a...