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The human Timeless-Tipin complex assures the replication fork protection ahea...
The accuracy of replication is one of the most important mechanisms ensuring stability of the genome. The fork protection complex prevents premature replisome stalling and/or... -
Replisome loading reduces chromatin motion independent of DNA synthesis
Chromatin has been shown to undergo diffusional motion, and during active gene transcription the RNA polymerase activity negatively affects chromatin motion. However, the...