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Influencing the Insulin System by Placebo Effects in Patients With Diabetes T...
This is a dataset from a randomized controlled trial on the pharmacological conditioning of intranasal insulin in healthy volunteers and patients with diabetes type-2 -
Structure and formation kinetics of insulin aggregates
We will use time-resolved SANS measurements to follow the self-assembly kinetics of insulin from protein monomers to fibrils. By measuring through a well-defined lag phase we... -
Early stages of amyloid aggregate formation
We will study the kinetics of the early stages of aggregate formation in protein solutions under conditions that are known to result in the formation of amyloid protein fibres... -
Investigation of the structure of self-assembling peptide fibrils using neutr...
A consortium of several UK universities and industries has been set up, based at the National Physical Laboratory, Teddington, to investigate ¿Length-scale bridging in... -
A SANS Study on the Influence of Shear on Peptide Fibrillisation
Time-resolved SANS will be performed to investigate the effect of shear on the fibrillisation of insulin following denaturation. The rheological response will be measured...