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Adsorption of an Anionic Surfactant on Anionic Surfaces in the Presence of Ca...
In this proposal we request beamtime on the Inter reflectometer to study the unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate caesium salt... -
AGGREGATION BEHAVIOUR OF A NOVEL P-AOT SURFACTANT
This proposal aims to provide essential surfactant micellisation structural information of significant interest in its own right but also as key information for our on-going... -
Polymer conjugates for drug delivery
Complex polymer architectures such as comb polymers have been studied for their highly customisable chemical properties. Potential applications have been identified in a wide... -
Interactions between Designed Antimicrobial Lipopeptides and Inner Membrane L...
Neutron reflection will be used to reveal the structural changes from different inner membrane leaflet models upon interacting with a group of antimicrobial lipopeptides with... -
Solution aggregation of lipopeptides: SANS structure determination
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Adsorption of Organic Phosphate onto Silicon
This proposal presents to directly measure ¿bridging¿ of anionic surfactants on an anionic surface through multivalent ions from water under well-controlled conditions (pHs and... -
Surface adsorption in hydrophobin and hydrophobin / surfactant mixtures
Hydrophobins are secreted fungal proteins and are small lipopeptide biosurfactants. They are strongly surface active and self-assemble at interfaces. Their unique film forming... -
Elucidating molecular mechanism of membrane disruption by designed α-hel...
We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also... -
Solution Aggregation of Short Peptide Amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading interfacial adsorption and solution nano-aggregation.... -
Co-adsorption of monoclonal antibodies and non-ionic surfactants at the air/l...
Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in a binary mixture with protein. However, we show... -
Interactions between a polymer brush grown from a macro-initiator-modified sa...
We propose to make neutron reflectivity measurements of the weak polyelectrolyte, poly(dimethy amino ethyl methacrylate), grown from two different surface densities of initiator... -
Effect of high temperatures on the adsorption of benzotriazole onto copper/co...
Benzotriazole (BTAH) is a very effective corrosion inhibitor for copper and its alloys in both water and in oils. BTAH is introduced as a corrosion inhibitor in oil based... -
Self-assembly of beta-casein and beta-casein / hydrophobin mixtures
Hydrophobins, hfb2, are secreted fungal proteins in the form of a small lipopeptide. They are strongly surface active and self-assemble in solution and at interfaces. They have... -
Structural study on the 3D arrangement of (hexa-acyl) lipid A in lipid membrane
This study will focus on the structural investigations of the bilayers formed on silicon substrates in which the outer leaf consists of DOPE/LPS mixtures. We aim is to achieve...