We investigated the influence of corticosterone release rates on survival of larval Northern Leopard Frogs (Rana pipiens) chronically exposed to four different concentrations of salinity (NaCl). The dataset contains mean values for snout-vent length (mm), mass (g), developmental stage (Gosner stage) and mean log-transformed corticosterone release rates (baseline, stress-induced, and corticosterone increase; pg/h). It also contains survival data in percent surviving, numbers alive and dead, and total number of larvae per day and treatment