This is a hydrographic dataset containing CTD cast and rosette bottle data from two consecutive cruises (NEG2017 and NorthGreen) on the research vessel RV Dana between 23-08-2017 and 01-10-2017 of 2017 on the Northeast Greenland shelf. Both cruises took place between 73.3197 to 80.0519 latitude and 2.1011 to 21.2039 longitude (decimal).The NEG2017 cruise took place from 23 August 2017 to 11 September 2017 was part of the Strategic Environmental program for Northeast Greenland with as its goal to provide environmental impact information pertaining to potential oil exploitation and oil spill response activities in the region. The cruise leader for NEG2017 was Eva Friis Møller.The NorthGreen2017 cruise took place directly after the first between 11 September 2017 and 1 October 2017. It aimed to collect data pertaining to hydroraphical and environmental changes on the shelf. The cruise leader for the NorthGreen2017 cruise was Marit-Solveig Seidenkrantz.