The purpose of this study is to perform expression profile of globalwide genes under control condition, and when exposed to 0.1 mg/L Microplastics and 0.5 mg/L Microplastics. The results from this study gives insight on the specific and common genes expressed under experimental groups on Oxidative stress/anti-oxidant pathways, energy metabolic pathways, growth regulating pathways, detoxification pathways, ion-regulation pathways and immune response pathways.