The prevalence, evolution and chromatin signatures of plant regulatory elements

Chromatin accessibility and modification is a hallmark of regulatory DNA, which has led to the discovery of cis-regulatory elements (CREs). Here, we characterize chromatin accessibility, histone modifications and sequence conservation in 13 plant species. We identified thousands of putative CREs and revealed that distal CREs are prevalent in plants especially in species with large and complex genomes. The majority of distal CREs have been moved away from their target genes by transposable element (TE) proliferation, but a significant number of distal CREs also appear to be created by TEs. Finally, plant distal CREs are associated with three major types of chromatin signatures that are distinct from metazoans. Taken together, these results suggest that CREs are prevalent in plants, highly dynamic during evolution, and function with distinct chromatin pathways to regulate gene expression. Overall design: Examination of Chromatin accessibilities, different histone modifications, and expressions in 13 plant species.

Identifier
Source https://data.blue-cloud.org/search-details?step=~01290B258D905CD5764B0823F1D186B9E7972CD481E
Metadata Access https://data.blue-cloud.org/api/collections/90B258D905CD5764B0823F1D186B9E7972CD481E
Provenance
Instrument NextSeq 500; ILLUMINA
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2024
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Temporal Point 2019-09-22T00:00:00Z