The dataset presented here includes four .csv files with primary archaeobotanical, large mammal bone, mollusc and fish remains data, recovered during the PALAP project at Palaikastro, east Crete, Greece, between 2013 and 2015. The data describe bioarchaeological remains from the south-east sector of the Bronze Age town at Palaikastro, recovered with systematic sampling and employing flotation, dry-sieving and hand collection. All remains were identified and quantified using established methodologies and were then stored at the premises of the British School at Athens in Crete (Ayios Antonios centre, Palaikastro). The dataset will be of use to archaeologists working in the Aegean and beyond and can contribute to key debates related to the Bronze Age, such as the emergence and economic organisation of urban centres.