Membrane interactions of a viral scission protein

DOI

Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus lifecycle are the processes that mediate the formation of new viruses and their release from the host cell by membrane scission. Recently we have found a novel role for the influenza virus M2 protein in virus budding, the mediation of membrane scission. The aim of this research is to investigate the molecular details of how M2 alters the shape of the membrane. This will be determined by studying the interactions of the M2 protein with a lipid membrane using neutron reflectivity.

Identifier
DOI https://doi.org/10.5286/ISIS.E.67771054
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/67771054
Provenance
Creator Dr Jeremy Rossman; Dr Basma Bahsoun; Dr Luke Clifton; Ms Agnieszka Martyna
Publisher ISIS Neutron and Muon Source
Publication Year 2018
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering
Temporal Coverage Begin 2015-11-07T09:00:00Z
Temporal Coverage End 2015-11-09T09:00:00Z