Proof of principle: Can ecotoxological partition constants for persistant organic pollutants between water and proxy lung lining be measured

DOI

A proof-of-principle experiment to use the convenient scattering length of perfluorinated alkyl surfactants to measure partitioning to lipids at the air-water interface, representative of lung ling. The partitioning of Perfluorooctadecanoic acid and perfluorooctadecanoic sulphate to a monolayer of the lipid DPPC at the air-water interface will be measured at biological temperature as a function of perfluorinated compound concentration. The partition constant and adsorption kinetics will be measured and will be used in ecotoxicological models to understand the bioaccumulation of perfluorinated surfactants in biological organs.

Identifier
DOI https://doi.org/10.5286/ISIS.E.67776091
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/67776091
Provenance
Creator Miss Francesca Brady; Dr Arwel Hughes; Professor Martin King
Publisher ISIS Neutron and Muon Source
Publication Year 2018
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Chemistry; Natural Sciences
Temporal Coverage Begin 2015-11-07T09:00:00Z
Temporal Coverage End 2015-11-09T09:00:00Z