Influence of Alkyl Chain Fluidity on the Membrane Binding Activity of Cationic Surfactants


Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improves patient compliance and can provide a release for long periods of time. One of the greatest challenges for transdermal delivery is that only a limited number of drugs can penetrate the skin by this route. This proposal will focus on the interaction between the model membrane and surfactants, and try to understand the influence of surfactant fluidity. This work may contribute to the surfactant-based transdermal drug delivery system in the future.

Metadata Access
Creator Mr Zi Wang; Dr Kun Ma; Dr Peixun Li; Dr yao chen; Dr John Webster; Dr Mario Campana
Publisher ISIS Neutron and Muon Source
Publication Year 2023
Rights CC-BY Attribution 4.0 International;
OpenAccess true
Contact isisdata(at)
Resource Type Dataset
Discipline Biology; Biomaterials; Chemistry; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering; Natural Sciences
Temporal Coverage Begin 2019-10-10T08:00:00Z
Temporal Coverage End 2020-03-11T08:44:33Z