Dynamic transition of Poly(ethylene glycol) with or without the solvation water

DOI

Water is the source of life, but the effects of hydration water on the dynamics and function of biological and bio-compatible macromolecules are still full of debates. Chen et al. found a dynamic transition of the solvation water at about 220 K, and claimed that such a liquid-liquid transition of water command the dynamic and function of the proteins. However, Hong and colleagues found out that dry perdeuterated protein also experience a dynamic transition at about 200 K by quasi-elastic neutron scattering. To clarify the problem, a direct observation of the dynamics of the hydration layer about macromolecule in the transition process is crucial. Here, we propose quasi-elastic neutron scattering of dry Poly(ethylene glycol) (PEG) and PEG solvated with a single layer of water bellow and up the liquid-liquid transition of confined water at about 200 K.

Identifier
DOI https://doi.org/10.5286/ISIS.E.RB1920340-1
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/108676002
Provenance
Creator Dr Victoria Garcia Sakai; Dr He Cheng; Mr SONGWEN XIAO; Dr Taisen Zuo; Dr Guisheng Jiao; Dr CHANGLI MA; Mr XIONG LIN
Publisher ISIS Neutron and Muon Source
Publication Year 2022
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering
Temporal Coverage Begin 2019-12-13T08:30:00Z
Temporal Coverage End 2019-12-20T07:52:31Z