Land-atmosphere interactions at different temporal and spatial scales are important for our understanding of the Earth system and its modeling. The Landscape Evolution Observatory (LEO) at Biosphere 2 managed by the University of Arizona host three nearly identical artificial bare-soil hillslopes with dimensions of 30m x 11m and 1m average depth in a controlled and highly monitored environment under a large greenhouse. These facilities provide a unique opportunity to explore these interactions. This dataset contains, for each one of the three replicate hillslopes, 15-minute measurements from July 1, 2015 to June 30, 2019 of temperature, water content and heat flux of the soil at a depth of 5cm for 12 co-located points; temperature, relative humidity and wind speed above ground at 5 different locations over each hillslope and 5 different heights ranging from 0.25m to 9-10m; 3D wind components at 1 location; the 4 components of radiation at 2 different locations; precipitation rates; and the measurements of an automatic weather station outside the greenhouse.