Fecal 16S rRNA sequencing and metabonomics Reveals Abnormal Metabolism Activity in Preterm infants with different gestational ages

In recent years, the research on the human gut microbiome has emerged as a critical research priority[1]. The gut microbiota exists in a harmonious community within the human intestinal tract, where it metabolizes lipids, proteins, and indigestible substances while also producing short-chain fatty acids [2]. With advancements in 16S ribosomal RNA (rRNA) gene analysis of fecal samples, gut dysbiosis has been observed in various diseases including inflammatory bowel disease, pneumonia, mastitis, cancer, metabolic syndrome, and allergic diseases[3 4]. Gut dysbiosis leads to the destruction of the intestinal mucosal barrier which can enhance susceptibility to pathogens and result in infection occurrence [5].

Identifier
Source https://data.blue-cloud.org/search-details?step=~012C7C5B18260AFC3F99D718F0E9871C68A9E9C21A7
Metadata Access https://data.blue-cloud.org/api/collections/C7C5B18260AFC3F99D718F0E9871C68A9E9C21A7
Provenance
Instrument Illumina NovaSeq 6000; NextSeq 500; ILLUMINA
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2024
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Temporal Coverage Begin 2021-06-01T00:00:00Z
Temporal Coverage End 2022-01-09T00:00:00Z