Locating proteins in curved lipid bilayers

DOI

Non-lamellar lipid phases are known to play important roles in-vivo and have attracted enormous interest as biocompatible scaffolds in applications form drug delivery to membrane protein crystallisation. Here we aim to locate preferential partitioning of three proteins to the flat and curved (saddle) points within bicontinuous cubic phases respectively. This will be vital to unlocking our ability to exploit the biotechnical potential of these structures.

Identifier
DOI https://doi.org/10.5286/ISIS.E.94114732
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/94114732
Provenance
Creator Miss Zexi Xu; Dr Adam Squires; Miss Eleonore Mason; Dr Oscar Ces; Dr Nick Brooks; Dr Sarah Rogers; Dr Arwen Tyler
Publisher ISIS Neutron and Muon Source
Publication Year 2021
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Chemistry; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering; Natural Sciences
Temporal Coverage Begin 2018-07-04T08:00:00Z
Temporal Coverage End 2018-07-07T09:00:31Z