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Heterogeneous protein exchange at the solid/liquid interface using deuterated...
The formation of protein layers on surfaces is important for medical implants and for the consequences of the ingestion of nanoparticles. In the body, a surface is exposed to a... -
Inelastic neutron scattering from H_2 in binary clathrate hydrates
The proposing team is interested in exploring the rotational and translational dynamics of molecular hydrogen trapped in water-based cages (clathrate hydrates). These systems... -
How an olefin adsorbs at a catalyst's surface and its implications to the che...
Metal and metal oxide nanostructures can be prepared in much different morphology (nanowires, nanobelts, nanofibres etc.) which are known to exhibit better adjustable properties... -
PROBING DRUG PHARMACODYNAMICS BY INS - THE EFFECT OF CISPLATIN-LIKE ANTICANCE...
Cancer is a growing health problem worldwide, and thus the development of effective chemotherapeutic approaches is crucial for improving human health. Much effort has been put... -
Hydrothermal synthesis and calcination of hydrotalcites
Hydrotalcites are anionic clays which have a variety of applications, including use as environmentally friendly catalysts and catalyst precursors. In this experiment we propose... -
Deuteration-induced phase transition in a multiferroic framework material
The hybrid organic-inorganic perovskites are of great interest as functional materials, because they combine the well-established perovskite topology with new physics and... -
Partially deuterated gradient poly(2-oxazolines): self-assembly studies
Gradient and block copoly(2-oxazoline)s have been prepared comprising a partially deuterated hydrophilic poly(2-methyl-2-oxazoline) part and a hydrogenated... -
Solution aggregation of short peptide surfactants
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
Studying the lateral organisation of mixed phospholipid bilayers by diffuse n...
Off-specular neutron reflection is potentially a powerful technique for studying the lateral organisation of phospholipid bilayers. However, this has not yet been demonstrated.... -
Investigations of atomic and intermediate-range structure in model membranes
This proposals aims to investigate the atomic and intermediate range structure in model membrane environments. By beginning with a disperse system of a phosphocholine lipid in... -
Interaction between Rubisco and SDOBS at an air-water interface
Protein-surfactant interactions at an interface play an important role for broad applications in the chemical, dairy, cosmetic and pharmaceutical industries. Rubisco is the most... -
Magnetic Properties of Rare-Earth Carbonates
We have prepared a new family of rare-earth carbonates, R4(CO3)6(H2O)2en (R=Dy-Lu). With the exception of R=Er, all materials exhibit a steadily decreasing meff below 70K. The... -
Examination of the Membrane Structure of Live Bacteria using Neutron Reflecto...
We propose to investigate in-vivo cell membrane structure of gram-positive (B. subtilis) and gram-negative (S. oneidensis) bacteria adhered to a silicon oxide surface using... -
Effects of Architecture on Polymer Diffusion
As part of a wider study we are studying the effects of polymer architecture between cyclic and linear polymers. From ATR-FTIR measurements we observe clear differences between... -
Structural development during crystallisation of synthetic polymers
We wish to exploit the unique capability of Nimrod to move forward the long standing issue of the way in which long chain polymers crystallise. There are two key length scales:... -
Phase separation in confined polymer blends studied by SERGIS
We intend to study the phase separation morphology of confined polymer blends. Interface forces will impose morphologies different from those in the bulk. In our experiments the... -
Quantifying the adsorption of lecithin on sucrose particles to understand cho...
Small angle neutron scattering will be used to directly quantify the adsorption of lecithin at the interface between partially deuterated sucrose particles contrast-matched to a... -
Interaction of Chiral Amino Acids and Sugars with Hydrated Vermiculite Clay
This proposal aims to provide an atomistic understanding of the adsorption of chiral amino acids and sugars on mineral surfaces using isotopically labelled reagents. Our... -
Single-crystal analysis of disorder in deuterated and protonated mirabilite
Mirabilite (Na2SO4.10H2O) is relevant to many areas of geology, planetary science, and even the construction industry. It occurs naturally in evaporite deposits, and even as... -
Nature of the protein corona on nanoparticle surfaces
When nanoparticles enter a biosytem they rapidly acquire a protein corona. The nature of the outer part of this corona will determine the response of the biosystem to the...