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Interfacial conformation of antibody and antigen binding capacity
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Part B: Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic l...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Proof of principle: Can ecotoxological partition constants for persistant org...
A proof-of-principle experiment to use the convenient scattering length of perfluorinated alkyl surfactants to measure partitioning to lipids at the air-water interface,... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of... -
Structure of Colloidal Crystals Near a Solid Surface
The structure of colloidal crystals (dispersions of particles that spontaneously order in a regular array) is known to be influenced by solid boundaries. However there are few... -
Co-adsorption and competitive adsorption of eggshell membrane polypeptide aga...
In this work we explore how to use neutron reflection to study the interfacial adsorption from a natural eggshell membrane polypeptide at the oil/water interface. We will then... -
Manipulating surface adsorption of SLES surfactants using temperature
Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we... -
Understanding the true biological function of Plant Non Specific Lipid Transf...
Non specific lipid transfer proteins are a family of basic, cysteine rich proteins found in a wide range of plant species. The biotechnological role of these proteins in beer... -
SANS studies of phospholipid:sterol vesicles and the membrane interactions of...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Interaction of Surfactant with Model Lipid Membranes: Influence of Surfactant...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improve patient compliance and can provide release for long... -
Part A: Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic l...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Part B: Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic l...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Interactions of modified clupeines with Gram-negative model bilayers
Clupeine is isolated from herring and is an example of a protamine, which are cationic antimicrobial peptides occurring in the sperm cells of some fish. Protamines are active... -
Neutron reflection from nanoparticles interacting with insoluble monolayers
Cell-nanoparticle interactions are complex, involving several specific and non-specific intermolecular forces between a wide range of particulate and molecular species . There... -
A model of the bacterial outer membrane containing both Outer Membrane Protei...
We have recently improved the stability and coverage of free standing bilayers (FSB) by the use of a supporting thiolipid layer on gold. The system has been investigated on... -
Molecular interactions between phospholipid monolayers and dimethylsulphoxide
Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a... -
Structural characterization of a series of polymer-protein conjugates for chr...
Polymer-protein conjugates have been designed to deliver an appropriate target growth factor to promote a more rapid healing of chronic wounds, an incredibly important area for... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface.... -
Investigating a Dextrin-Phospholipase A2 Conjugate as a Trigger for Polymer E...
Recent research has demonstrated the potential of nanosized delivery systems for routine use in many diseases, eg cancer, viral diseases and rheumatoid arthritis [1,2], due to...