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Structure of Confined Albumin Layers
In the context of a project in collaboration with ISIS that focuses on structural studies under mechanical confinement, with a specific focus on biological lubricants, the... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Adsorption of hydrophobin at the oil/water interface
Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how another globular protein hydrophobin adsorbs at the oil/water interface by... -
Neutron reflectometry of an atopic dermatitis stratum corneum skin model
Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting up to 20% of children and 3% of adults, resulting in significant reduction in quality of life and costs... -
Lipid exchange between high density lipoprotein (HDL) and model phosphatidylc...
Lipoproteins are the main carriers of lipids in the body. HDL is believed to favor cholesterol removal and decrease the risk to develop atherosclerosis and related... -
Warm Polar Cloud Chemistry: Can the Halogen "explosion" effect cloud droplet ...
The oxidative processing of pollutants in Polar clouds affects droplet size and optical properties. Polar clouds contain naturally occurring organic lipids forming organic films... -
Interaction of Low Density Lipoproteins (LDL) with Model Mammalian Cell Membr...
Atherosclerosis and subsequent clinical complication is one of the biggest killers in the western world, with a death toll reaching 16.7 million deaths per year. Although many... -
Depth profiles in bulk heterojunction films containing low-molecular weight o...
Neutron reflectivity will be used to investigate the composition in the direction perpendicular to the substrate for films of blends of electron-donor... -
Determination of Organic Friction Modifier conformation under shear
Engine oils act to lubricate and protect moving parts in an engine. They act to reduce friction and reduce emissions. A major class of friction reducing additives are organic... -
A study of the role of divalent cations in the stability of smooth LPS in out...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaires disease. It is important as; a barrier to antibiotics & the site of... -
Organic Additives Adsorption at the Steel-Paint Interface and Its Effects on ...
Numerous additives have been added to paints and coatings to improve adhesion, and prohibit corrosion if the substrate is reactive to its surrounding environs. The adsorbates in... -
Effect of glycolipids with therapeutic potential on phase behaviour of model ...
alpha-galactosylceramide (a-GalCer) can activate an immune response through a protein-mediated cell signalling event. The effect of a-GalCer on local membrane structure is... -
Adsorption of magnetic surfactants
Surfactants responsive to pH, temperature, CO2, and light are known, however, our recent work has shown, for the first time surfactants that are magneto-responsive, and also... -
Anionic surfactant induced desorption of cationic surfactants from anionic su...
In this proposal, we request beamtime to study the unexpected behaviour of a strongly bound bilayer of the cationic surfactant didodecyldimethylammonium bromide on the anionic... -
Structure of Confined Mucin Films
Nowadays, a significant research effort is devoted to understand and mimic biological lubricants which, in contrast to most man-made lubricants, are based on water. It has been... -
The effect of membrane fluidity on the interaction of antimicrobial proteins ...
Protein-lipid\membrane interactions are fundamentally important to biological processes. We have examined the role protein hydrophobicity in protein-membrane interactions... -
Mimicking Pathogens : Floating Gram Negative Bacterial Membranes Containing t...
Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies.... -
Structure and encapsulation of additives in spray coated surfactant templated...
This proposal continues our work into surfactant templated films formed from surfactant/polyelectrolyte solutions. Recently we have been studying the encapsulation of... -
Heterogenous reactions between gas-phase hydroxyl radicals and organic films ...
Projected climate change is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and reflectivity, important climatic effects.... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of...