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Temperature Effects and Kinetics of Thiolipid Adsorption to Gold Surfaces
We have a programme investigating the structure and function of protein scaffolds oriented on gold surfaces using sulfur chemistry for attachment. The aim is to direct the... -
The interpenetration of two poly(ethylene oxide) polymer brushes under confin...
Coating two surfaces with polymer brushes has been shown on many occasions to reduce friction by orders of magnitude. These ultra-low frictions are believed to stem from be the... -
Tuneable Adsorption of Soft Colloids on Model Biomembrane
Understanding how nanoparticles interact with lipid bilayers will potentially have high impact on the development of new drug delivery systems, and on the investigation of their... -
pH Responsive Polymer Blend Surfaces
Polymers, end-functionalised with carboxylic acid (COOH) groups do not normally segregate to film surfaces due to the high surface energy of these functionalities. However, we... -
Startup and Calibration
This dataset has no description
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Assembling floating, very sparsely tethered, protein-lipid bilayers.
We have recently used Polref in to measure the assembly of tethered floating lipid bilayers. These are useful models of biological membranes in which a phospholipid bilayer is... -
quenching and partitioning the new heat-treatment process 44
quenching and partitioning the new heat-treatment process 44 -
Adsorption Structures of Organics additives at the Iron/Oil Interface and the...
Numerous chemical additives have been added to steel surfaces to improve adhesion, and prohibit corrosion if the substrate is reactive to its surrounding environs. This... -
Incommensurate-commensurate phase transitions in K2SeO4
Materials with incommensurate structures often show exotic properties (such as charge density waves). The development of reliable and efficient refinement techniques for such... -
In-situ internal strain measurements in textured austenitic steel under strai...
Internal strains and dislocation microstructures can dramatically affect the mechanical performances of metallic alloys. Then deformation mechanisms and physical properties must... -
The interaction of novel gold supraparticles with model lipid membranes
Engineered nanoparticles (NPs) found large application in medicine as theranostic materials for the diagnosis and therapy of many diseases. The understanding of the interactions... -
Polymerisation of Styrene in PEI-Surfactant Films on Si Wafers
We have been studying the formation of solid polymer-surfactant films formed from cationic surfactants with PEI. We wish to use the highly organised mesostructures formed in the... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
The role of disulphide bridges in the adsorption of globular proteins at the ...
Following our previous study of adsorption of globular lysozyme and BSA at the oil/water interface by neutron reflection, we continue to explore how unfolding of globular... -
Interfacial Adsorbtion from Nematic Mixtures
The aim is to determine the amount of absorbtion of the one component of a mixture at the nemtic/air interface using neutron reflection. The host material in the mixture will be... -
Testing protein location in curved lipid bilayers using oriented lipid cubic ...
This proposal will test whether membrane proteins within lipid cubic phases preferentially sit in more or less curved bilayer regions, using our recent advances in preparing... -
Membrane reconstitution of human dihydroorotate dehydrogenase using lipid-det...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
Cation ordering in silicate spinel Ni2SiO4
Silicate spinels are important minerals in the transition zone region of the Earth and in order to understand seismic signals from these depths (550-660 km) we need to know the... -
Seizing Membrane Proteins - Cytochrome P450 Reductase in Nanodiscs
This proposal seeks to shed light on the functional and structural characteristics of a specific membrane protein - cytochrome P450 reductase (abb. POR) - part of the cytochrome... -
Surfactant Adsorption in Multi Metal Deposition Fingerprint Enhancement
Multi metal deposition (MMD) is a new latent fingerprint enhancement technique that is extremely effective on plastics, including drug wraps and explosives wrapping; it is also...
