149 datasets found

Toxoplasma gondii is a unicellular eukaryote belonging to the Apicomplexa phylum. It is an obligate intracellular parasite of critical importance to primarily infected pregnant...

The apicomplexan parasite Toxoplasma gondii is cosmopolitan in nature, largely as a result of its highly flexible life cycle. Felids are its only definitive hosts and a wide...

The positioning of chromosomes in the nucleus of a eukaryotic cell is highly organized and has a complex and dynamic relationship with gene expression. In the human malaria...

Coenzyme A (CoA) is an essential and highly versatile molecule acting in metabolism, post-translational modification, and regulation of gene expression. While all organisms...

The Toxoplasma gondii G1 RESTRICTION checkpoint operates the switch between parasite growth and differentiation. The Cdk-related G1 kinase TgCrk2 forms alternative complexes...

The protozoan pathogen Toxoplasma gondii has the unique ability to develop a chronic infection in the brain of its host. The T. gondii develops cysts within the neurons that are...

Ingestion of Toxoplasma gondii results in life-long infection due to its ability to convert from the rapidly disseminating tachyzoite stage to the chronic, encysted bradyzoite...

Drug treatment group

Characterization of apicomplexans polyadenylation sites

Transcriptome analysis of Vero cells infected with T.gondii RH strain

Developmental regulation of the intracellular parasite Toxoplasma gondii is an understudied topic despite being central for a bid to control its dissemination around the globe....

Toxoplasma gondii is an intracellular parasite that relies on intricate molecular mechanisms for its proliferation and survival. Here, we investigate the role of TgUAE1 in these...

The goal is to determine the Function of F-Box proteins in Toxoplasma gondii, specifically TgFBXL2 which is nuclear localized and its knockdown affects the parasite gene...

T.gondii strain RH Delta UPRT ELQ-316 mutant Genomic data

ApiAP2 are a family of conserved transcription factors (TF) that play an important role in regulating gene expression in apicomplexan parasites. ApiAP2 proteins that may control...

To understand the interaction between host cell and the Toxoplasma gondii bradyzoite at a transcriptomic landscape. We sought to characterize the host cell response induced by...

The apicomplexan parasite Toxoplasma gondii can infect humans and almost all warm-blooded animals worldwide, poses significant threat to the public health and of veterinary...

Here, using direct RNA sequencing and Illumina RNA sequencing, we show that AP2XII-1 and AP2XI-2, two transcription factors expressed in tachyzoites, a stage that causes acute...

Resequencing of Bumped kinase inhibitor (BKI) resistant Toxoplasma gondii clones established from strain PLK/DUAL by chemical random mutagenesis. 250 and 1000 nM 1NM-PP1 were...

Transcriptomics analysis of Toxoplasma gondii after AP2XII-9 depletion