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RNA sequencing of host transcriptome of human foreskin fibroblast cells infec...
The purpose of these data is to determine if the impact bradyzoites have on the host transcripton is dependent on the export of parasite effector proteins via Myr1. We found... -
Experimental Evolution of Toxoplasma gondii
High-throughput targeted amplicon-based Next Generation Sequencing (NGS) of Toxoplasma gondii RH strain during laboratory propagation in in vivo, in vitro and alternate models,... -
RNA-seq transcriptional profile of Toxoplasma gondii strains RH, PLK, CTG as ...
Using high through-put RNA sequencing, we assayed the transcriptomes of three different strains of Toxoplasma gondii representing three common genotypes under both in vitro... -
The transcription factor AP2XI-2 is a key negative regulator of Toxoplasma go...
Commitment to and completion of sexual development are essential for Toxoplasma gondii to produce oocysts in the intestine of the feline host. Understanding of the molecular... -
RNA-Seq of Toxoplasma GRX1mutation
The antioxidant protein glutaredoxin 1 is essential for oxidative stress response and pathogenicity of Toxoplasma gondii -
Transcriptome sequencing of WT and inorganic phosphate transporter (TgPiT) or...
Purpose: Toxoplasma must import inorganic phosphate via a transporter at the plasma membrane. Methods: WT and TgPiT-deficient parasites were grown in human foreskin fibroblasts... -
AP2XII-2 binding sites in Toxoplasma gondii
Developmental regulation of the intracellular parasite Toxoplasma gondii is an understudied topic despite being central for a bid to control its dissemination around the globe.... -
Toxoplasma gondii Transcriptome or Gene expression
Our study detects the transcriptomic differences upon depletion of protein disulfide isomerase TgPDI8 and TgPDI6 -
In vitro production of cat-restricted Toxoplasma pre-sexual stages by epigene...
Here we show that AP2XII-1 and AP2XI-2, two transcription factors expressed in tachyzoites, a stage that causes acute toxoplasmosis, silence genes specific to merozoites, a... -
Next-Generation Sequencing of KG8-Resistant T. gondii Clonal Isolates
Sequencing reads from single isolates of T. gondii randomly mutated through chemical mutagenesis to be resistant to experimental compound benzoquinone acyl hydrazone (KG8). -
Toxoplasma gondii
This dataset has no description
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Pseudouridines of Toxoplasma gondii and infected host cells
RNA from Toxoplasma-infected cells +/- CMCT to label and identify pseudouridines. Wild-type and pseudouridine-synthase-1 (PUS1)-mutant parasites were used for comparison purposes. -
Comparative characterization of microRNA profiles of different genotypes of T...
The present study characterized comparatively the miRNA profiles of three different genotypes of T. gondii, identified genotype-shared miRNAs and strain-specific miRNAs. Overall... -
Characterization of the BFD2-bound transcriptome in chronic-stage T. gondii
The acute-to-chronic stage transition in Toxoplasma gondii involes a global restructuring of the parasite transcriptome and can be induced by alkaline stress. Prior work... -
Primary brain cell infection by Toxoplasma gondii reveals the dynamics of spo...
Toxoplasma gondii is a eukaryotic parasite that form latent cyst in the brain of immunocompetent individuals. The latent parasites infection of the immune privileged central... -
Transcriptional profiling of T. gondii and H. hammondi during in vitro develo...
Using transcriptomics to determine the genetics of virulence in Toxoplasma gondii -
Transcriptomics of Toxoplasma gondii enteroepithelial stages
Toxoplasma gondii is a zoonotic pathogen for which felids serve as definitive hosts. In cats, the parasite undergoes several rounds of asexual replication before entering the... -
Laboratory surveillance of Toxoplasma gondii in Portugal
High-throughput targeted amplicon-based Next Generation Sequencing (NGS) of Toxoplasma gondii human isolates detected in Portugal by the National Reference Laboratory of... -
Regulation of Toxoplasma growth and development by AMPK
Regulation of Toxoplasma growth and development by AMPK -
Dual RNA-seq analysis of pig alveolar macrophage infected with china-isolated...
Toxoplasma gondii is an apicomplexan parasite infecting human and animals, causing huge health concerns and economic losses. However, it is unclear about the exact mechanism of...
