19 datasets found

The interface of CaCO3 (calcite) and water is of paramount importance in a number of key academic and industrial areas, including scale deposition in domestic and industrial...

Following our very recent work on the dynamic co-adsorption of our control antibody COE-3 and nonionic surfactant PS80-7EO from the mixed solution, We request 3 days of Inter...

Following our previous study of interfacial adsorption of the basic version mAb COE-3, we wish to continue this work by exploring how two modified mAbs adsorb at the same...

The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to...

Heavily bio-engineered monoclonal antibodies (mAbs) are an increasingly important trend in the biopharmaceutical industry. However, these mAbs are often destabilised by the...

We wish to understand how the concentration of surfactant mixtures in solution affects adsorption at lower temperatures; in particular, we wish to see how the composition of the...

Neutron reflection will be used to reveal the structural changes from different inner membrane leaflet models upon interacting with a group of antimicrobial lipopeptides with...

Here we aim to structurally characterise the formation of adsorbed monolayers of heparin on calcite to address how these species influence biomineralisation and the inhibition...

The surface tension of proteins often exhibits a reproducible lagtime, which is sensitiv to a range of conditions such as concentration, pH, ionic strength. We have also found...

Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the...

Projected climate change is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and reflectivity, important climatic effects....

Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a...

This proposal constitutes part of our ongoing study towards understanding how keratin, an important protein component of hair and skin, interacts with ionic surfactants using...

Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in abinary mixture. However, we show in this work...

Following our previous study of adsorption of Fc, Fab and the constituent mAb COE-3, we continue to explore how two bioengineered mAbs adsorb at the oil/water interface by...

Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how another globular protein hydrophobin adsorbs at the oil/water interface by...

Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we...

We propose to use neutron reflection to study the interfacial adsorption of 2 novel bispecific therapeutic antibodies at the silicon oxide/water interface. To enpower each of...

We have previously studied the adsorption of anti-beta-hCG at the hydrophilic silicon oxide/water interface and the subsequent binding by antigen hCG. We propose to extend this...