35 datasets found

Pluronic micelles are attractive candidates as drug carriers. Despite the abundance of data on their association with various drugs, there is, in contrast, very little...

Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation or crosslinking resulting in lack of...

Soft self-assembled structures have been extensively used as drug nanocarriers. Their building blocks, naturally occurring and synthetic amphiphiles (lipids or block...

Ultrasound is a very attractive and patient-friendly imaging technique, as it is easy to use, fast and non-invasive. Nevertheless, its use is severely limited by the low...

Sodium deoxycholate (NaDC) is a low molecular weight gelator, widely known as one of the components of bile salts. Above a specific concentration, NaDC is able to form pH...

Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation, crosslinking resulting in lack of orientation...

Our group has been working functionalised cellulose nanofibrils which form gels in aqueous formulations. Previously we have used these fibrils to stabilise oil-in-water...

Large quantities of thermal energy can be stored reversibly in composite materials containing SrCl2 and Expanded Natural Graphite (ENG) upon exo-/endothermal ab-/desorption of...

Bacterial lipopolysaccharide (LPS) is a bioactive structural amphiphilic molecule which forms the outer leaflet of the outer membrane of the Gram negative cell envelope. During...

We have been developing hydroxypropylmethyl cellulose (HPMC) microspheres for delivering poorly water-soluble drugs. The in vitro dissolution data showed that the presence of...

In a previous proposal we started to study the micellar structures formed from biodegradable surfactants synthesised using amino acids as the headgroups. The aim of this work is...

Deep Eutectic Solvents (DES) are mixtures of an organic salt with a hydrogen bond donor that form strong interactions which hinder crystallisation. DES share many features with...

Zwitterionic lipids such as phosphatidylcholine (PC) are major components of the membranes that compartmentalize organisms. Although there is a large literature on PC, cationic...

The aim of the proposed experiment is to carry out a series of SANS measurements on chain-grafted silica nanoparticles prepared in our laboratory. In this experiment we plan to...

We intend to study the aggregation behaviour of the all-conjugated block catiocopolyelectrolyte PF2/6-P3MAHT in the presence of the biomacroanion guanosine triphosphate (GTP) in...

Water-soluble conjugated polymers (WSCP) are an important class of materials which have received great attention as active materials in optoelectronic devices and in biosensing....

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

The aim of this proposal is to study the structure of hydrogel systems formed from fluorenylmethyloxycarbonyl (FMOC) protected peptides, via the use of nitric oxide radicals....

This proposal constitutes part of our ongoing study towards understanding how keratin, an important protein component of hair and skin, interacts with ionic surfactants using...

This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the...