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Dataset for "Pediatric autoimmune uveitis is associated with intraocular anti...
This dataset contains the IgG antibody profile as measured using a peptide microarrays containing 3,760 linear B-cell epitopes from 196 human pathogens from 18 patients with... -
Solution structures of three immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Solution structures of the immunologically important proteins IgA, IgG and C3
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Protein interactions at solid-liquid interfaces: The effect of affinity colum...
Biopharmaceuticals are manufactured using chromatographic procedures including adsorption and desorption processes at the solid-liquid interface. These events take place in... -
Solution structures of the immunologically important proteins IgA and C3b
We are unravelling the solution structures of the Fab and Fc fragments in the IgA antibody family important in mucosal immunology. Having completed the structures for IgA... -
Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier... -
Neutron scattering to characterise protein interactions with solid-liquid int...
Objectives of this proposal aim to shed light on how adsorption processes such as protein A chromatography, used to purify biologics, affect protein propensity for aggregation.... -
Solution structures of the immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its...
