-
Y1000+ Saccharomycotina yeasts genome sequencing and assembly
Genomes from the Y1000+ project aiming at sequencing the genomes of all the known Saccharomycotina yeasts -
Genome-wide nucleosome position data for 12 yeast species
We mapped nucleosome positions genome-wide in 12 Ascomycetes Overall design: Illumina sequencing of mononucleosomal DNA isolated from mid-log cultures grown in rich medium... -
SFP1 (RNA-seq)
We measured global expression profiles in SFP1 deletion mutants and isogenic wild type strains during lag and log phase growth. To match the physiology of each species as well... -
SFP1 (ChIP-seq)
We set out to determine how Sfp1 binding targets evolved over time. We sampled our species of interest to include one pre-whole genome duplicaton (WGD) species containing SFP1A... -
Transcriptomic comparison of 11 species of yeast in rich media and oxidative ...
The objective of this experiment was to study the mechanism of de novo gene birth in Saccharomyces cerevisiae. While the model organism S. cerevisiae has one of the highest... -
The evolution, evolvability, and engineering of gene regulatory DNA [RNA-seq]
Here, we used RNA-seq to quantify expression conservation across many Ascomycete yeasts. Overall design: We used strand-specific RNA-seq (dUTP) to quantify mRNA expression in... -
Intron evolution in Saccharomycetaceae
Purpose: Saccharomyceatacea yeast are intron-poor species and they contain on average 300 introns in their genomes. We designed RNAseq experiment to investigate if splicing... -
Small RNAs in budding yeast
RNAi, a gene-silencing pathway triggered by double-stranded RNA, is conserved in diverse eukaryotic species but has been lost in the model budding yeast, Saccharomyces... -
Regulation of DNA replication time is crucial for appropriate gene expression
Eukaryotic genomes are replicated in a reproducible temporal order, however, the physiological significance is poorly understood. We compared replication dynamics in divergent...