35 datasets found

We mapped nucleosome positions genome-wide in 12 Ascomycetes Overall design: Illumina sequencing of mononucleosomal DNA isolated from mid-log cultures grown in rich medium...

This study uses population genomic data to estimate demographic and selection parameters in two sister lineages of the wild yeast Saccharomyces paradoxus and compare their...

N6-methyladenosine (m6A) is the most abundant mRNA modification, primarily implicated in controlling mRNA stability. The distribution of m6A varies considerably between and...

We have applied deep Illumina sequencing to 12 natural strains of S. cerevisiae and S. paradoxus to complement the PacBio sequencing that we performed for these strains. Please...

Determining how transcriptional regulation had evolved in the course of yeast speciation.

Hybrids between species frequently suffer from reduced fertility. Following the propagation of 672 yeast lines through 770 mitotic generations in which natural selection was...

The budding yeast Saccharomyces cerevisiae is a long-standing model for the three-dimensional organization of eukaryotic genomes1,2, and recent high-throughput chromatin...

We profiled the transcriptomes of four Saccharomyces species, as well as pairwise hybrids between three of the species with S. cerevisiae Overall design: For pairwise...

The nonrandom distribution of meiotic recombination shapes heredity and genetic diversification. A widely held view is that individual hotspots - favored sites of recombination...

In the past we have sequenced a variety of S. cerevisiae and S. paradoxus yeast strains with both capillary and Illumina sequencing (Nature 2009) and used them for functional...

This project aims to identify factors driving evolution of intron-lacking genes

DNA replication initiates from defined locations called replication origins some origins are highly active whereas others are dormant and rarely used. Origins also differ in...

SGRP, the Saccharomyces Genome Resequencing Project, is a collaboration between the Sanger Institute and Prof. Ed Louis' group at the Institute of Genetics, University of...

Killer toxins are extracellular antifungal proteins that are produced by a wide variety of fungi, including Saccharomyces yeasts. Although many Saccharomyces killer toxins have...

Whole Transcriptome Sequencing of Saccharomyces cerevisiae YPS2073, YPS2079 Saccharomyces paradoxus YPS3395, YPS3434

We measured global expression profiles in SFP1 deletion mutants and isogenic wild type strains during lag and log phase growth. To match the physiology of each species as well...

We applied the ribose-seq and Ribose-Map techniques to study biological signatures of ribonucleotide incorporation in the genomic DNA of budding and fission yeast. We found that...

We set out to determine how Sfp1 binding targets evolved over time. We sampled our species of interest to include one pre-whole genome duplicaton (WGD) species containing SFP1A...

Ribosome profiling was performed on interspecific hybrids of Saccharomyces cerevisiae and S. paradoxus in order to identify allele-specific expression indicative of...

The objective of this experiment was to study the mechanism of de novo gene birth in Saccharomyces cerevisiae. While the model organism S. cerevisiae has one of the highest...