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Temperature Effects and Kinetics of Thiolipid Adsorption to Gold Surfaces
We have a programme investigating the structure and function of protein scaffolds oriented on gold surfaces using sulfur chemistry for attachment. The aim is to direct the... -
Incommensurate-commensurate phase transitions in K2SeO4
Materials with incommensurate structures often show exotic properties (such as charge density waves). The development of reliable and efficient refinement techniques for such... -
Water librations in proton conducting hydrated alkali thio-hydroxogermanates
We propose to perform a systematic study of the intermolecular librational mode of molecular water in the proton conducting hydrated alkali thio-hydroxogermanates... -
RF-mSR study of high-Ge Si1-xGex alloys
Single crystal, bulk Si1-xGex alloys are available across the alloy composition range, and provide opportunity for study of alloy properties in transition between the two... -
Measuring strains in geologically important hydrous minerals
We request 4 days of beam-time on ENGIN-X to measure the elastic behaviour of polycrystalline samples of gypsum, antigorite, and talc as a function of uniaxial load. All three... -
Study of Co- and Fe-doped and undoped hafnium oxide tunnel barrier structures
We propose to investigate with polarized neutron reflection (PNR) measurements the magnetic moment and interface properties of Co- and Fe-doped HfO2 thin films and undoped HfO2... -
Interaction between Rubisco and SDOBS at an air-water interface
Protein-surfactant interactions at an interface play an important role for broad applications in the chemical, dairy, cosmetic and pharmaceutical industries. Rubisco is the most... -
Investigation of carrier transport in the organic semiconductor 8-hydroxy-qui...
Using the Emu spectrometer at ISIS we have recently studied charge carrier transport in the technologically important molecule 8-hydroxy-quinoline aluminium, by probing the... -
Effect of pH on the shape of oil-in-water microemulsions formed by a zwitteri...
Despite interest in microemulsions as drug delivery vehicles, there is a lack of structural understanding to justify the formulations used. The present study examines the use of... -
Microscopic structure of acetic acid in water and methanol
Some of the most important chemical reactions involve Brønsted acids and bases where the solvation structure and transport dynamics of charged defects in hydrogen-bonded... -
Solution structures of three immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Thermal ionization of bond-centred muonium in diamond
Our previous LF-µSR measurements in natural type Ia single crystal diamond showed some evidence of the ionization of bond-centred muonium (MuBC) from around 1000K. This was... -
Solution structures of the immunologically important proteins IgA, IgG and C3
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Novel proton environments in geologically important hydrous silicates
Hydrous chain silicates (amphiboles) are central to understanding many geological processes in the Earth¿s Crust, Upper Mantle and Transition Zone, where they influence melting,... -
Evidence for a Diffuse Interfacial Region at the Dichloroethane/Water Interface
The 1,2- dichloroethane (DCE)/water interface is important because of its suitability as an electrochemical interface between two immiscible electrolyte soloutions. An issue of... -
Inelastic magnetic scattering in CePd3
CePd3 is a classic intermediate valence (IV) system. In MAPS experiment 620167 we obtained an important qualitative result for CePd3, namely that the Kondo-like scattering... -
SANS Investigation on Packing Structure of Proteasome Activator 28
Proteasome plays an important role in the processing of antigenenic proteins for presentation by the MHC class I pathway. PA28 is an activator of the 20S proteasome, a large... -
Solution structures of the immunologically important proteins IgA and C3b
We are unravelling the solution structures of the Fab and Fc fragments in the IgA antibody family important in mucosal immunology. Having completed the structures for IgA... -
Mechanical twinning in quartz rocks: in situ experiments at stress and during...
Previous experiments at ENGIN-X (Wenk et al. 2007) established that quartz rocks undergo mechanical twinning if stressed above 100 MPa. The amount of twinning is highly... -
Mesostructured titania films from ethanolic solutions
In this proposal we wish to continue our current work on mesostructured inorganic films in largely ethanolic solutions, containing limited amounts of water. Transition metal...
