53 datasets found

It is difficult for the naked external gene to become internalized due to its similar charge to the extracellular membrane surface. Various cationic copolymers and cationic...

Polymers, end-functionalised with carboxylic acid (COOH) groups do not normally segregate to film surfaces due to the high surface energy of these functionalities. However, we...

We have synthesised alkyl phosphorylcholine (CnPC) surfactants in hydrogenated and deuterated form and have determined their solution aggregation using SANS. In this part of...

Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug...

The formation of multilayer structures at surfaces and interfaces from self-assembly in mixed surfactant and in polymer / surfactant mixtures has been recently reported, and...

Hydrophobins are secreted fungal proteins in the form of small lipopetide biosurfactants. They are strongly surface active and self assemble at interfaces and in solution. This...

We have previously used LOQ to identify the complex (polyplex) structures formed between a short single strand DNA and a cationic diblock copolymer MPC30-DEA60. The SANS...

Summary. Silicatein in marine sponges catalyses the condensation of silica but the mechanism of layer-by-layer growth of the silica spicule is unknown since sufficient...

The spontaneous formation of multilayer structures at interfaces by surfactant self-assembly is emerging as an important and more common structural signature associated with a...

Hydrophobins are secreted fungal proteins in the form of small lipopetide biosurfactants. They are strongly surface active and self-assemble at interfaces and in solution. This...

The strong interaction between polyelectrolytes and ionic surfactants can result in pronounced surface adsorption and the formation of surface multilayer structures. This...

This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the...

In this proposal we request beamtime on the Inter reflectometer to study the unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate caesium salt...

New detergents will increasingly rely on sustainable products and the use of enzymes will become ever more important. However, the process of destruction of stains (often...

Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug...

In a recent EPSRC / Unilever / Oxford CASE project we have used NR to explore and develop optimised delivery mechanism for active benefit agents such as perfumes. In particular...

We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing...

Biological membranes do not only occur as planar bilayer structures, but bilayers have also been shown to, depending onthe lipid composition, curve into intriguing 3D...

The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to...

Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and...